*A pluripotential target is

defined as a protein with a molecular function that contributes to the initiation, activation, or progression of the majority of cellular signaling pathways that are activated in cells involved in a specific disease process.
It is essential that the inhibition of these proteins does not raise safety concerns. Consequently, their inhibitors can safely control activated cells through the inhibition of the activated pathways, regardless of which pathway or combination of pathways are activated during the disease process.