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Platform Technology: Drugging Informatics™

At PimedBio, we’ve developed a cutting-edge platform technology called "Drugging Informatics™", designed to discover innovative drug candidates that can effectively manage the complex signaling pathways involved in challenging diseases like cancer and immune-mediated inflammatory diseases (IMIDs).

What is Drugging Informatics™?

"Drugging Informatics™" is an advanced informatics approach that leverages big data to uncover new drug targets driving multiple disease-related pathways according to disease contexts, and design therapies to inhibit these target. This platform is especially tailored for treating diseases with complex origins, where traditional treatments often fall short.

How does it work?

Our platform operates in two key phases:
Target Discovery
In this phase, we focus on identifying proteins by analyzing large-scale biological data to pinpoint those involved in multiple pathways related to disease progression. Notably, these targets do not activate all disease-related pathways simultaneously; instead, they trigger only the pathways relevant to specific disease contexts. Consequently, inhibiting these proteins can safely and effectively control the disease, regardless of which pathways are active at any given time. This approach enables us to discover targets capable of regulating several signaling pathways at once, tailored to the disease context. Therefore, such proteins are ideal candidates for the development of drugs to treat complex and heterogeneous diseases.
Innovative Drug Design
Once we’ve identified these key targets, we move to the drug design stage. Here, we deeply analyze the target proteins to develop drug candidates that can modulate these proteins optimally. Our design process focuses on understanding the relationship between a drug’s structure and its activity, ensuring that the final product is both effective and safe. We explore various strategies, including drugs that inhibit multiple pathways, protein degraders, inhibitors of protein-protein interactions, peptidomimetic drugs, bispecific small molecules, and inhibitor-drug-conjugates.
Pluripotential Target Discovery
Innovative Drug Design

Why is Drugging Informatics™ Important?

"Drugging Informatics™" offers an integrative approach to managing diseases that involve complex and varied signaling pathways. By targeting the root causes of these pathways, our technology enables the creation of drug candidates that can effectively treat diseases that have been difficult to manage with conventional therapies.
Through this innovative platform, PimedBio is leading the way in developing next-generation therapies that promise to make a significant impact on the treatment of intractable diseases.